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The sociodemographic and clinical characteristics of the study population are described in detail in Table 1, and Beyer et al

NAD + depletion elevates the methylation of BDNF promoter, triggering the dissociation of the DNA methylation-sensitive nuclear factor CCCTC-binding factor (CTCF) and cohesin from the BDNF locus

& Lai, S

The secretion of antimicrobial peptides by Paneth cells is regulated by susceptibility genes and depends on microbiota interactions [183], while the loss of transcription factor EB (TFEB) in colonic epithelium weakens the antioxidant barrier [184]